Mane has taken a decisive step into the future of natural sweetening with its acquisition of the exclusive global licence to produce and commercialise Arzeda’s ViaLeaf Reb M, marking a significant evolution in how high‑performance sugar‑reduction solutions reach the market.

Under the expanded partnership, Mane now controls the entire Reb M value chain — from production through formulation and commercial deployment — creating a single, integrated pathway for manufacturers seeking reliable, scalable and economically viable sugar‑reduction ingredients. The move builds on the collaboration announced earlier this year and positions both companies at the forefront of next‑generation sweetener innovation.

ViaLeaf Reb M is the first ingredient enabled by AI‑driven protein design to reach commercial scale. Arzeda’s computational technology has reshaped the economics of Reb M production, delivering a steviol glycoside prized for its clean, sugar‑like sweetness and neutral flavour profile. By pairing this breakthrough with Mane’s global manufacturing and flavour‑creation capabilities, producers gain access to a Reb M solution designed for industrial deployment rather than niche application.

Samantha Mane, CEO of the Mane Group, said the agreement reflects the company’s commitment to delivering “innovative, high‑performance solutions” to customers. With Mane overseeing production, flavour development and application support, manufacturers can expect a consistent supply of Reb M with strong taste performance and competitive cost‑in‑use — two factors that have historically limited the adoption of natural sweeteners at scale.

For producers, the partnership offers a scalable, reliable and commercially competitive route to sugar reduction at a time when global demand for lower‑sugar products continues to accelerate. The integrated model reduces formulation complexity, supports clean‑label development and enables brands to reformulate across multiple categories with greater confidence in supply and performance.

Arzeda CEO Alexandre Zanghellini described Mane as “uniquely positioned to unlock the full potential of ViaLeaf Reb M,” emphasising that the combination of AI‑enabled ingredient design and industrial‑scale production will accelerate adoption across the food and beverage sector.

By merging technological innovation with global manufacturing strength, Mane and Arzeda are setting a new benchmark for natural sweetening solutions — one that gives producers a clearer, more economically viable pathway to delivering sugar‑reduced products without compromising taste.